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Roy S Herbst, MD, PhD Chief, Section of Thoracic Medical Oncology Associate Professor of Medicine Co-Director, Phase I Clinical Trials Working Group Department of Thoracic, Head and Neck Medical Oncology The University of Texas MD Anderson Cancer Center Houston, Texas

Edward S Kim, MD Assistant Professor of Medicine Director, Educational Programs Department of Thoracic, Head and Neck Medical Oncology The University of Texas MD Anderson Cancer Center Houston, Texas

CONTENT VALIDATION AND DISCLOSURES

Research To Practice is committed to providing its participants with high-quality, unbiased and state-of- the-art education. We assess potential conflicts of interest with faculty, planners and managers of CME activities. Real or apparent conflicts of interest are identified and resolved by a peer review content validation process. The content of each activity is reviewed by both a member of the scientific staff and an external independent reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.

The scientific staff and consultants for Research To Practice are involved in the development and review of content for educational activities and report the following real or apparent conflicts of interest for themselves (or their spouses/partners) that have been resolved through a peer review process: Richard Kaderman, PhD, Neil Love, MD, Douglas Paley, Michelle Paley, MD, Margaret Peng, Lilliam Sklaver Poltorack, PharmD, Carol R Regueiro, MD, MSc and Kathryn Ault Ziel, PhD — no real or apparent conflicts of interest to report; Marie Bialek, PharmD — Freelance/Contract Medical Writer: McNeil Consumer & Specialty Pharmaceuticals, Janssen Pharmaceutica Products LP; Salary (spouse): AstraZeneca Pharmaceuticals LP; Sally Bogert, RNC, WHCNP — shareholder of Amgen Inc. Research To Practice receives education grants from Abraxis Oncology, Amgen Inc, AstraZeneca Pharmaceuticals LP, Biogen Idec, Genentech BioOncology, Genomic Health Inc, Roche Laboratories Inc and Sanofi- Aventis, who have no influence on the content development of our educational activities.

In addition, the following faculty (and their spouses/partners) have reported real or apparent conflicts of interest that have been resolved through a peer review process:

Dr Herbst — Consulting Fees: Amgen Inc, AstraZeneca Pharmaceuticals LP, Eli Lilly and Company, Genentech BioOncology; Speakers Bureau: Amgen Inc, AstraZeneca Pharmaceuticals LP, Eli Lilly and Company, Genentech BioOncology; Contracted Research: Amgen Inc, AstraZeneca Pharmaceuticals LP, Eli Lilly and Company, Genentech BioOncology. Dr Kim — Consulting Fees: Genentech BioOncology, Sanofi-Aventis; Fees for Non-CME Services Received Directly from Commercial Interest of Their Agents: Genentech BioOncology, Sanofi-Aventis; Contracted Research: Genentech BioOncology, Sanofi-Aventis.

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This educational activity contains discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.

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